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A sequence of 28S rRNA-derived small RNAs is enriched in mature sperm and various somatic tissues and possibly associates with inflammation Free
Chen Chu1,†, Lu Yu1,†, Bin Wu2, Li Ma3, Lan-Tao Gou4, Miao He5, Yunli Guo3, Zhi-Tong Li1, Wei Gao6, Huijuan Shi2, Mo-Fang Liu1, Hongyan Wang3, Charlie Degui Chen1, JoelR.Drevet7, Yuchuan Zhou1,*, and Yonglian Zhang1,*
1State Key Laboratory of Molecular Biology, Shanghai Key Laboratory of Molecular Andrology, CAS Center for Excellence in Molecular Cell Science, Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences, University of Chinese Academy of Sciences, Shanghai 200031, China
2China National Population and Family Planning Key Laboratory of Contraceptive Drugs and Devices, SIPPR, Fudan University,Shanghai 200032, China
3State Key Laboratory of Molecular Biology, CAS Center for Excellence in Molecular Cell Science, Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences, University of Chinese Academy of Sciences, Shanghai 200031, China
4Department of Cellular and Molecular Medicine, University of California, San Diego, La Jolla, CA 92093-0651, USA
5Institute of Neuroscience, State Key Laboratory of Neuroscience, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031, China
6Department of Geratology, Shanghai General Hospital, Shanghai Jiaotong University, Shanghai 200080, China
7Genetics Reproduction & Development Laboratory, CNRS UMR6293–INSERM U1103– Universite´ Clermont Auvergne, Clermont- Ferrand, France
†These authors contributed equally to this work. *Correspondence to:Yonglian Zhang, E-mail:ylzhang@sibcb.ac.cn; Yuchuan Zhou, E-mail:zhouych@sibs.ac.cn
J Mol Cell Biol, Volume 9, Issue 3, June 2017, 256-259,  https://doi.org/10.1093/jmcb/mjx016

The growing understanding concerning the definition, classification, and function of small non-coding RNAs (sncRNAs) has led to the discovery of new sncRNA species of various sizes. Recent studies highlighted a group of tsRNAs derived from the 5′ end of tRNAs (Peng et al., 2012; Zhang et al., 2014; Chen et al., 2016; Sharma et al., 2016), which raises the question whether there are similar small RNAs derived from other housekeeping RNAs, such as rRNAs.


Volume 9, Issue 3
June 2017